Manchester United visit Tottenham Hotspur at White Hart Lane on Sunday 20th January 2013 (KO 16:00) in the 23rd round of matches in the 2012-13 season.
Spurs come into the match in 4th place on 40 points with United in first place on 55 points.
It will be the 183rd meeting between the two clubs who were the "glamour teams" of the 1960s.
Tottenham Hotspur's first meeting with Manchester United came in the old 1st round (today's 3rd round) of the FA Cup in January 1899 when United were known as Newton Heath. The match was drawn 1-1 at Northumberland Park, but Spurs won the replay 5-3 at Bank Street in Clayton, Manchester.
A decade later the two clubs met for the first time in a Football League match with United drawing 2-2 at White Hart Lane in the First Division.
The reverse fixture at Old Trafford was easilly won by United 5-0.
Tottenham's first League win over United came in November 1911 2-1 at Old Trafford.
Both clubs met for four seasons in the Second Division during the 1930s.
Since the start of football after WW2, all League meetings have taken place in the Top Flight of the English League system.
In 1952, both clubs toured North America and played two exhibition matches with Spurs winning 5-0 in Toronto, Canada and 7-1 in New York, USA.
The clubs were drawn together in the 1963-64 European Cup Winners' Cup with Spurs winning 2-0 at the Lane and United winning 4-1 at Old Trafford.
Old Trafford was the venue for the 1967 FA Charity Shield with League Champions United and FA Cup Winners Spurs drawing 3-3 in a game most remembered for goalkeeper Pat Jennings' long-range goal. The Charity Shield was shared.
August 1979 saw the clubs meet for the first time in the Football League Cup and Glenn Hoddle's magnificent volly was the winning goal in a 2-1 Spurs victory at White Hart Lane. United went on to win the second leg at Old Trafford 3-1.
In June 1983, the clubs played two matches in Swaziland, Southern Africa, resulting in a win each. Prior to this season, Spurs last win at Old Trafford came in December 1989 thanks to a Gary Lineker goal.
The clubs have only ever met in one Domestic Cup Final - the 2009 Football League (Carling) Cup Final at Wembley, which ended in a 0-0 draw after extra time. United won the subsequent penalty shoot-out.
Manchester United and Tottenham Hotspur were founder members of the Premier League in 1992-93 and are two of the seven clubs who have been ever-present up to the 2012-13 season - Woolwich, Aston Villa, Chelsea, Everton and Liverpool being the other five.
The fixtures during season 2010-11 saw United win 2-0 at Old Trafford in October while the reverse match at White Hart Lane ended in a 0-0 draw.
2010-11 was the first season when both Manchester United and Tottenham Hotspur competed together in the UEFA Champions League. Both clubs won their respective Group Stages and progressed to the Knock-Out Phase. Spurs eventually went out to Real Madrid in the Quarter Finals while Manchester United made it to the Final, only to lose to Barcelona.
The away fixture at Old Trafford last season in August resulted in a 3-0 win for United with goals from Danny Welbeck, who headed in Tom Cleverley's cross just after 60 minutes and he then produced a wonderful instinctive flick to set up a second for Anderson. Wayne Rooney scored with a pinpoint late header from Ryan Giggs's centre.
The game at White Hart Lane in March 2012 was won by United 3-1. Wayne Rooney scored on the stroke of half-time to put the visitors ahead at the break. Further goals were added with a brace from Ashely Young before Jermain Defoe got one back for Spurs with three minutes remaining.
This season's earlier fixture at Old Trafford resulted in an historic 3-2 win for Tottenham - their first in the League at Old Trafford in 23 years. Jan Vertonghen's second minute strike was deflected-in off Jonny Evans and Gareth Bale added a second goal after 32 minutes. United hit back through Luis Nani after 51 minutes but Spurs restored their two goal cushion a minute later with a Clint Dempsey goal. Shinji Kagawa scored United's second goal a minute later and Spurs survived the pressure for a United equaliser to come away with three very well earned points.
Former Manchester United defender Zeki Fryers joined Spurs in January 2013 from Standard Liege in Belgium.
Overall, United have a very good record over Spurs with 86 wins to 50 with 46 of the 182 matches played so far drawn.
They Played for United & Spurs....
David Beckham (United player, Spurs trainee)
Greoge Graham (United player, Spurs manager)
Stewart Houston (United player, Spurs asst. manager)
David Gwilan Jones
Joe Jordan (United player, Spurs coach)