Yeah absolutely. Especially as, while it's annoyingly limited and imbalanced, we do actually have a deep squad (most teams line-ups would actually look significantly worse than ours with 10+ first team injuries).
We should be able to get about 80-100m for prize assets like Romero and VdV alone. And before people say we'd be forced to sell them for peanuts, remember Newcastle got 30m for Sissoko and 25m for Wijnaldum when they were relegated TEN years ago. We'd have to sell for below market value but we could still command solid fees.
Main thing would be gutting the squad of negative influences and players not up for the fight in the Champ. I suspect Kudus, Xavi and probably Tel would try to force moves and they're also pretty high wage earners. That's probably another 80-100m for those 3.
Beyond that we're really not gonna be forced to sell. That's 4-5 big wage earners and 150-200m in transfer fees. Other sales should be made for squad balancing purposes and to reinvest in the squad.