"HYA also inhibits gastric Helicobacter infections by blocking the bacterial futalosine pathways. "
N6 is actually what the body converts into HYA = 10-hydroxy-
cis-12-octadecenoic acid.
If you are medical, of course you will look at H.Pylori, but looking at it from a biochemistry viewpoint it is further back along the regulatory chain which makes the host susceptible, or as I see it the real cause.
I'm a very, very amateur scientist (emphasis very, very)...
Edit : Fledgling research areas, but here are some further:
Supplemental feeding of a gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid (HYA), alleviates spontaneous atopic dermatitis and modulates intestinal microbiota in NC/nga mice.
Japan leading on this stuff it seems.
More:
Highlights
• A gut microbial metabolite of
linoleic acid (HYA) elicits
anti-inflammatory effects in vitro
.• HYA down-regulates the Lipopolysaccharide-induced maturation of bone marrow dendritic cells (DCs).
• HYA treatment associated with an anti-inflammatory profile in
murine enterocyte and in mature DCs.
• HYA up-regulates cytoprotections in murine enterocyte and in mature DCs.
• HYA is considered a functional component in foods and pharmaceutical products.
Various hydroxy-, oxo-, and conjugated fatty acids are generated by gut microbes throughout the metabolism of dietary PUFAs. Specifically, 10-Hydroxy-…
www.sciencedirect.com
Anyway, hope NDombele has a good dietary lipid profile...