If we play Dembele-Mason-Bentaleb, Stambouli-Mason-Bentaleb or Dembele-Mason-Bentaleb without both Kane and Soldado in the team we will be asking for trouble because Chelsea will know we offer very little threat going the other way. I've always thought the best form of defending is offering some sort of attacking threat and that's what we currently have going into this game. Taking that away from us peels us back to what is essentially a mismatch in midfield quality and we will go down without a whimper by 3 or more goals
The lone striker will get isolated, the middle of the pitch will get congested although that won't bother fabregas much and we'll get murdered down the flanks. On the flip side of that it's hard to say for sure without seeing their starting 11. I just really don't wanna see Dembele play as he pretty much operates in his own little world were he's Modric.