Point taken that Athletico are exceptional defensively, and their success won't necessarily translate to other teams. At the same time, it's not normal for teams to have the % assists Liverpool get from full back. So I wonder if some of their success is due to exploiting modern tactical trends of teams setting up to dominate/win the centre eg 433. I'm not tactically knowledgeable enough to judge that, but formations tend to come in and out of vogue.
2 up top also worked well for us. Seems to get the best out of Kane, whether it's Dele or Son playing close to him.