Sissoko for Lo Celso and Lucas (or maybe Bale ) for Lamela.
Why would you want Sissoko for Lo Celso?
There is nothing he does better than Lo Celso and plenty that he does worse.
I would also hope that the Lucas starting nonsense is done with how poor he has been but I worry that he is a golden boy so expect we will see more of him.
Unless you are saying that Jose would make those changes and not you, which is fair enough.